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Epicardial adipose tissue may predict new-onset atrial fibrillation in patients with ST-segment elevation myocardial

Hayati Eren1, Muhammed Bahadir Omar2, Ülker Kaya1

  • 1Department of Cardiology, Elbistan State Hospital, Kahramanmaraş.

Journal of Cardiovascular Medicine (Hagerstown, Md.)
|September 17, 2021
PubMed

Insights

Increased epicardial adipose tissue (EAT) thickness is a significant predictor of new-onset atrial fibrillation in ST-elevation myocardial infarction (STEMI) patients after primary percutaneous coronary intervention (pPCI). This finding suggests EAT thickness can serve as a valuable cardioembolic risk factor.

Area of Science:

  • Cardiology
  • Cardiac Imaging
  • Electrophysiology

Background:

  • Atrial fibrillation (AF) is a common complication following ST-elevation myocardial infarction (STEMI).
  • Epicardial adipose tissue (EAT) has been implicated in the pathophysiology of various cardiovascular diseases.
  • The role of EAT thickness in predicting AF development post-STEMI requires further elucidation.

Purpose of the Study:

  • To investigate the relationship between epicardial adipose tissue (EAT) thickness and the incidence of new-onset atrial fibrillation (AF) in patients with STEMI.
  • To determine if EAT thickness is an independent predictor of AF development in the post-primary percutaneous coronary intervention (pPCI) period.

Main Methods:

  • A cohort of 413 STEMI patients undergoing pPCI was studied.
  • EAT thickness was measured using transthoracic echocardiography.
  • Logistic regression analysis was employed to identify independent predictors of AF.

Main Results:

  • Patients who developed AF had significantly higher EAT thickness compared to controls (P < 0.001).
  • EAT thickness was positively correlated with the SYNTAX score (r = 0.523, P < 0.001).
  • Logistic regression identified EAT thickness as an independent predictor of AF (OR: 4.135, 95% CI: 1.245-8.176, P < 0.001).

Conclusions:

  • Epicardial adipose tissue thickness is a significant marker for AF development in STEMI patients post-pPCI.
  • EAT thickness may serve as a useful cardioembolic risk factor in this patient population.
Abstract

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