Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Autoregulation of Blood Flow

Autoregulation of Blood Flow

Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Two-Stage Reconstruction of Large and Ptotic Breasts in Patients Undergoing Risk-Reducing Mastectomy: A Single Center Experience Using Autologous Tissue.

Plastic and aesthetic nursing·2026

Same author

A Rare Case of Cutaneous Intraneural Glomus Tumor.

Journal of cutaneous pathology·2025

Same author

End to end versus end to side microvascular anastomosis for traumatic lower limb free flap reconstructions: A systematic review and meta-analysis.

Journal of hand and microsurgery·2024

Same author

Safety of Breast Liposuction and Oncologic Considerations.

Aesthetic plastic surgery·2024

Same author

A Blast and Burn Hand Injury Caused by an Exploding Vaping Device in a Pediatric Patient: A Case Report.

Plastic and aesthetic nursing·2024

Same author

Simultaneous Sentinel Lymph Node Biopsies Using Both the Magtrace/Sentimag System and Radioactive Isotope Tracer/Blue Dye Dual Technique for Concurrent Breast Carcinoma and Malignant Melanoma.

Eplasty·2024

Same journal

Improving assessment of post-exercise hypotension as a predictor of training efficacy.

International journal of sports medicine·2026

Same journal

Neuromuscular electrical stimulation after anterior cruciate ligament reconstruction.

International journal of sports medicine·2026

Same journal

Exercise Intensity Effects on Irisin in Master Athletes and Links With Maximal Oxygen Uptake and Body Fat.

International journal of sports medicine·2026

Same journal

Evolution of the Australian Institute of Sport Supplement Program over the last 25 years.

International journal of sports medicine·2026

Same journal

Preseason Passive Torque Asymmetries in Soccer Players with Hamstring Strain Injury.

International journal of sports medicine·2026

Same journal

Musculoskeletal Burden in German Equestrians: Hip-Specific Symptoms and Risk Factors.

International journal of sports medicine·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Oct 19, 2025

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow

Published on: December 15, 2023

Tolerance to Intermittent vs. Continuous Blood Flow Restriction Training: A meta-Analysis.

Pierre Sinclair¹, Murtaza Kadhum², Bruce Paton¹

¹Department of Institute of Sports and Exercise Health (ISEH), University College London, London, United Kingdom of Great Britain and Northern Ireland.

International Journal of Sports Medicine

|September 17, 2021

Summary

This summary is machine-generated.

Intermittent cuff deflations during blood flow restriction training do not improve exercise tolerance or strength gain. This method may not enhance recovery compared to continuous application in rehabilitation settings.

More Related Videos

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement

Published on: February 22, 2022

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice

Published on: February 2, 2019

Related Experiment Videos

Last Updated: Oct 19, 2025

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow

Published on: December 15, 2023

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement

Published on: February 22, 2022

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice

Published on: February 2, 2019

Area of Science:

Exercise Physiology
Rehabilitation Science
Sports Medicine

Background:

Low-load blood flow restriction training (BFRT) is recognized for its benefits in strength gain.
Its application in rehabilitation is explored due to limitations with heavy loads.
Low-load BFRT may be less tolerated than heavy-load resistance training.

Purpose of the Study:

To determine if intermittent cuff deflation during BFRT improves exercise tolerance.
To assess if intermittent cuff deflation compromises strength gains compared to continuous BFRT.

Main Methods:

A systematic review and meta-analysis of randomized controlled trials (RCTs) were conducted.
Searched four databases for studies comparing intermittent versus continuous BFRT in adults.
Nine studies were identified; six were included in the meta-analysis focusing on exercise tolerance and strength.

Main Results:

No significant difference in the rate of perceived exertion between intermittent and continuous BFRT (SMD -0.06, 95% CI -0.41 to 0.29, p=0.73).
Subgroup analysis excluding biased studies suggested a potential, though not statistically significant, benefit for intermittent BFRT (SMD -0.42, 95% CI -0.87 to 0.03, p=0.07).
No significant differences in strength gain were observed between the two methods.

Conclusions:

Intermittent cuff deflations during rest intervals of BFRT do not enhance exercise tolerance.
The strategy of intermittent cuff deflation does not appear to compromise strength gains.
Current evidence does not support intermittent BFRT as a superior method for improving tolerance in rehabilitation.