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MIS-C with diarrhea complaint and acute kidney injury: A pediatric COVID-19 patient

Sevcan İpek1, Ufuk Utku Güllü2, Sadık Yurttutan3

  • 1Department of Pediatrics, Kahramanmaraş Sutcu Imam University, Faculty of Medicine, Kahramanmaraş, Turkey.

Progress in Pediatric Cardiology
|September 20, 2021
PubMed

Insights

A 3-month-old infant with congenital heart disease developed severe dehydration and acute kidney injury due to COVID-19. The infant later deteriorated from multisystem inflammatory syndrome in children (MIS-C) and died, highlighting MIS-C as a critical diagnosis.

Area of Science:

  • Pediatric critical care medicine
  • Infectious diseases
  • Nephrology

Background:

  • A 3-month-old male infant with pre-existing congenital heart disease on furosemide and captopril presented with severe dehydration and acute kidney injury (AKI).
  • The AKI was initially attributed to COVID-19 infection.

Observation:

  • Despite initial improvement with hydration, the patient rapidly deteriorated on the fourth day of hospitalization.
  • The deterioration was diagnosed as severe multisystem inflammatory syndrome in children (MIS-C).

Findings:

  • The infant's condition worsened progressively despite maximal medical support.
  • The patient ultimately succumbed to severe MIS-C.

Implications:

  • Multisystem inflammatory syndrome in children (MIS-C) is a serious, potentially fatal complication of COVID-19 in infants.
  • MIS-C should be strongly considered in the differential diagnosis of pediatric patients presenting with acute kidney injury during the COVID-19 pandemic.

Keywords:
Acute kidney injuryCOVID-19Congenital heart diseaseDiarrheaMIS-C

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