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Related Experiment Video

Updated: Oct 19, 2025

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat
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Major Lower Limb Amputations: Recognizing Pitfalls.

Lemuel Pran1, Dave Harnanan2, Shanta Baijoo3

  • 1Vascular Surgery, Eric Williams Medical Sciences Complex, Mount Hope, TTO.

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|September 20, 2021
PubMed
Summary

Major lower extremity amputations are increasing in the Caribbean, primarily due to diabetes complications and sepsis. Few amputees receive prosthetic limbs, highlighting a critical gap in care.

Keywords:
diabetic foot complicationsdiabetic foot sepsislower extremity amputationmajor amputationmulti-disciplinary team

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Area of Science:

  • Vascular Surgery
  • Public Health
  • Diabetology

Background:

  • Major lower extremity amputations are a significant concern in the Caribbean.
  • Trends and contributing factors require urgent investigation.

Purpose of the Study:

  • To investigate current trends in major lower extremity amputations in Trinidad and Tobago.
  • To analyze yearly trends, demographics, amputation types, and reasons.

Main Methods:

  • Retrospective review of major lower extremity amputations from January 2010 to December 2016.
  • Analysis of yearly trends, gender, amputation level, and etiology.
  • Assessment of co-morbidities and prosthetic limb acquisition rates.

Main Results:

  • A progressive increase in amputation rates was observed (average 28 per 10^5/year).
  • Males constituted 59% of cases; 60% were above-knee amputations.
  • Sepsis (71.5%) was the primary reason; 91% had diabetes mellitus.
  • 52% had prior foot problems; only 14.5% acquired prostheses.

Conclusions:

  • Major limb amputations are rising in the region, despite vascular surgical unit establishment.
  • Diabetes and its foot complications are leading causes of amputation.
  • Low prosthetic limb acquisition rates indicate a significant unmet need.