Why are we vaccinating children against COVID-19?

Ronald N Kostoff1, Daniela Calina2, Darja Kanduc3

  • 1Independent Consultant, Gainesville, VA, 20155, USA.

Toxicology Reports
|September 20, 2021
PubMed

Insights

COVID-19 inoculations for children show a concerning risk-benefit ratio. Post-inoculation deaths in children, though small, are not negligible, raising long-term safety concerns.

Area of Science:

  • Pediatric Health
  • Infectious Disease Epidemiology
  • Vaccine Safety Research

Background:

  • COVID-19 mortality is significantly higher in the elderly with comorbidities compared to children.
  • Existing clinical trials for pediatric COVID-19 inoculations have limitations in duration, sample size, and population representativeness.
  • Long-term effects and biomarker changes post-inoculation in children remain understudied.

Purpose of the Study:

  • To critically evaluate the risk-benefit profile of COVID-19 inoculations in pediatric populations.
  • To assess the potential long-term implications of pediatric COVID-19 inoculations.
  • To compare inoculation-attributed risks versus COVID-19-attributed risks in children.

Main Methods:

  • Review of existing COVID-19 mortality data stratified by age.
  • Analysis of normalized post-inoculation mortality data.
  • A best-case scenario cost-benefit analysis comparing inoculation risks to disease risks.

Main Results:

  • COVID-19 attributed deaths per capita are negligible in children.
  • Normalized post-inoculation deaths in children are small but not negligible.
  • Cost-benefit analysis indicates a significantly higher risk of death from inoculation versus COVID-19 in the elderly (5:1 ratio), suggesting a less favorable ratio for children due to lower COVID-19 risk and unknown long-term effects.

Conclusions:

  • The current risk-benefit assessment for pediatric COVID-19 inoculations raises significant concerns due to minimal COVID-19 mortality in this age group and the unknown long-term consequences.
  • Further research into long-term safety, biomarker changes, and robust clinical trials with larger, representative pediatric samples are warranted.
  • The risk-benefit ratio for pediatric COVID-19 inoculations may be unfavorable, particularly when considering potential long-term adverse effects.

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