Single-Incision Versus Conventional Laparoscopic Appendectomy: A Multi-Center Randomized Controlled Trial (SCAR...

Area of Science:

• Surgical Innovation
• Minimally Invasive Surgery
• Clinical Trials

Background:

• Single-incision laparoscopic appendectomy (SILA) is technically challenging compared to conventional laparoscopic appendectomy (CLA).
• Evidence comparing SILA and CLA for patient outcomes like cosmetic satisfaction and pain is limited.
• Definitive criteria for selecting SILA over CLA in appendicitis patients are lacking.

Purpose of the Study:

• To compare the clinical benefits of SILA versus CLA for appendicitis treatment.
• To quantitatively assess cosmetic satisfaction and pain reduction between SILA and CLA.
• To provide evidence-based guidance for surgeons selecting appendectomy techniques.

Main Methods:

• A multi-center randomized controlled trial comparing SILA and CLA in a 1:1 ratio.
• Patients with appendicitis will be randomized to either CLA (3 ports) or SILA (single umbilical incision).
• Primary endpoint: cosmetic satisfaction (POSAS at 6 weeks). Secondary endpoints: pain (VAS, IPO), body image (BIQ), and complications.

Main Results:

• The study is a planned multi-center randomized controlled trial.
• It aims to recruit 120 patients to detect a 3-point difference in POSAS with 80% power.
• Data on cosmetic satisfaction, pain, and complications will be collected and analyzed.

Conclusions:

• This trial will generate robust evidence on the comparative effectiveness of SILA and CLA.
• Findings will inform clinical decision-making regarding the optimal appendectomy approach.
• The study aims to clarify the benefits of SILA for patient-reported outcomes.