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Updated: Oct 19, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Transition-Metal-Free Intramolecular Radical Aminoboration of Unactivated Alkenes
Danqing Zheng1,2, Kalipada Jana1, Fatmah Ali Alasmary3
1Organisch-Chemisches Institut, Westfalische Wilhelms-Universität, Corrensstraβe 40, 48149 Münster, Germany.
Abstract:
An efficient transition-metal-free cyclizing radical aminoboration of unactivated alkenes is reported. The B2(OH)4 reagent was used as the boron source, and the interaction between B2(OH)4 and an aryloxyamide N-radical precursor enabled the chain reaction to be initiated upon irradiation in the absence of any catalyst. This transformation proceeds via cyclization of an N-radical with subsequent intermolecular C-radical borylation. The cascade shows a broad scope and provides a wide range of high-value cyclic 1,2-aminoboronic esters.
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