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Updated: Oct 19, 2025

Tick Microbiome Characterization by Next-Generation 16S rRNA Amplicon Sequencing
Published on: August 25, 2018
Abstract:
Over the past two decades, tickborne diseases have demonstrated a steady rise in the United States, with several novel tickborne pathogens discovered. Tickborne illnesses vary by geography and seasonality secondary to the associated tick vector. Interestingly, the geographic range of these tick vectors are also expanding with many more counties reporting cases than the previous 20 years. The clinical presentation of tickborne infections can range from mild to fatal, thus early identification and empiric treatment is of utmost importance. This article reviews the most common tick-borne infections in the US, including epidemiology, clinical presentation, diagnosis, treatment, and prevention. [.
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