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Peripheral Nerve Entrapments in Cancer Pain
Rene Przkora1, Pavel Balduyeu2, Juan Mora2
1Division of Pain Medicine, Department of Anesthesiology, University of Florida College of Medicine, 1600 SW Archer Road, 100254, Gainesville, FL, 32610-0254, USA. rprzkora@anest.ufl.edu.
Cancer Treatment and Research
|September 20, 2021
Summary
Peripheral nerve entrapments are an under-recognized cause of cancer pain, often stemming from tumor invasion or cancer treatments. Prompt diagnosis and targeted interventions by pain specialists can significantly improve patient outcomes and quality of life.
Area of Science:
- Pain Medicine
- Neurology
- Oncology
Background:
- Peripheral nerve entrapments are a common source of pain, affecting patients globally.
- In cancer patients, nerve entrapments can arise from tumor invasion, surgical procedures, chemotherapy, or scarring.
- This specific cause of cancer pain is frequently overlooked, leading to delayed or inadequate treatment.
Purpose of the Study:
- To highlight the significance of peripheral nerve entrapments as a cause of cancer pain.
- To emphasize the importance of accurate diagnosis for effective pain management in cancer patients.
- To underscore the role of interventional pain physicians in managing these complex cases.
Main Methods:
- Diagnosis involves a comprehensive patient history and physical examination.
- Utilizes imaging studies and nerve conduction studies for assessment.
- Includes diagnostic nerve injections or blocks to confirm entrapment sites.
Main Results:
- Nerve entrapments can manifest as burning, tingling sensations (paresthesias), potentially leading to sensory and motor deficits.
- Accurate diagnosis is crucial for selecting appropriate treatments and avoiding ineffective interventions.
- Effective management by pain specialists can lead to substantial pain relief and enhanced quality of life.
Conclusions:
- Peripheral nerve entrapments are a significant and under-recognized contributor to cancer pain.
- A multidisciplinary approach involving pain specialists is essential for optimal management.
- Timely diagnosis and targeted treatment of nerve entrapments improve patient outcomes and reduce reliance on high-dose opioids.
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