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Updated: Oct 19, 2025

A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
Differences in partial oxygen saturation obtained from three pulse oximeters
Luis Efrén Santos-Martínez1, Martha Vianey Ureña-Plascencia2, Javier Quevedo-Paredes2
1Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Cardiología, Departamento de Hipertensión Pulmonar y Corazón Derecho.
Pulse oximeter variability was assessed in 255 patients. Onyx II and Hergom devices showed low variability, while the Rossmax SB220 exhibited significant variability, making it unsuitable for clinical use.
Area of Science:
- Medical Devices
- Clinical Measurement
- Respiratory Medicine
Background:
- Variability in partial oxygen saturation measurements exists between different pulse oximeters.
- Accurate oxygen saturation monitoring is crucial for patient care.
Purpose of the Study:
- To evaluate and compare the measurement variability of three distinct pulse oximeters in a clinical setting.
- To determine the reliability of different pulse oximeter devices for patient monitoring.
Main Methods:
- A cross-sectional study involving 255 consecutive patients.
- Demographic, occupational, and disease data were collected.
- Variability was assessed using Bland-Altman analysis and intraclass correlation coefficient (ICC).
Main Results:
- The study included patients with a mean age of 61 years, predominantly female and smokers, with COPD being a common condition.
- Onyx II and Hergom pulse oximeters demonstrated low measurement variability (ICC > 0.949).
- The Rossmax SB220 showed substantial variability (ICC = 0.784), indicating poor agreement.
Conclusions:
- Onyx II and Hergom pulse oximeters are reliable for clinical use due to their low variability.
- The Rossmax SB220 is not recommended for clinical practice owing to its high measurement variability.
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