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Related Concept Videos

Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
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There have been five major extinction events throughout geological history, resulting in the elimination of biodiversity, followed by a rebound of species that adapted to the new conditions. In the current geological epoch, the Holocene, there is a sixth extinction event in progress. This mass extinction has been attributed to human activities and is thus provisionally called the Anthropocene. In 2019 the human population reached 7.7 billion people and is projected to comprise 10 billion by...
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Conservation of Small Populations02:04

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Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
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Related Experiment Video

Updated: Oct 19, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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SARS-CoV-2 Delta Variant among Asiatic Lions, India.

Anamika Mishra, Naveen Kumar, Sandeep Bhatia

    Emerging Infectious Diseases
    |September 21, 2021
    PubMed
    Summary

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant was found in Asiatic lions in India. Increased surveillance of SARS-CoV-2 in wild animals is recommended to prevent the spread of concerning variants.

    Keywords:
    Asiatic lionsCOVID-19Delta variantIndiaSARSSARS-CoV-2coronaviruscoronavirus diseaserespiratory infectionssevere acute respiratory syndrome coronavirus 2viruseszoonoses

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    Area of Science:

    • Veterinary Virology
    • Wildlife Disease Ecology
    • Genomic Surveillance

    Background:

    • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has demonstrated zoonotic potential, with documented spillover events into various animal species.
    • In May 2021, SARS-CoV-2 was identified in a population of Asiatic lions housed in a zoological park in India.

    Discussion:

    • Phylogenetic analysis confirmed the presence of the B.1.617.2 (Delta) variant, a significant variant of concern, within the affected lion population.
    • This finding highlights the potential for SARS-CoV-2 variants to infect and circulate within wildlife populations, posing a risk to both animal and potentially human health.

    Key Insights:

    • The identification of the SARS-CoV-2 Delta variant in Asiatic lions underscores the importance of monitoring wildlife for emerging infectious diseases.
    • This case provides critical data on the susceptibility of non-domesticated felids to SARS-CoV-2 variants.

    Outlook:

    • Enhanced genomic surveillance programs for SARS-CoV-2 in wild animal populations are crucial for early detection and mitigation of disease transmission.
    • Proactive monitoring can help prevent the establishment of novel viral reservoirs in wildlife and reduce the risk of further zoonotic events.