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Published on: April 28, 2013
Kidney Transplant Cortical Necrosis Observed During Pelvic Radiation Therapy
Arunima Jain1, Apsara Windsor2, Angela Chou3
1Department of Renal Medicine, Gosford Hospital, Gosford, New South Wales, Australia.
Abstract:
A 61 year-old female kidney transplant recipient developed radiologic and biopsy-confirmed cortical necrosis in her transplant with elevated serum creatinine levels during concurrent chemoradiation therapy for anal squamous cell carcinoma. Acute anatomic and pathologic changes within a transplanted kidney during chemoradiation therapy have not been described previously in the literature. Further research is required to ascertain the potential significance and long-term clinical consequences of such findings.
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