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Ureteric obstruction in renal allograft recipients
South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
|December 24, 1977
Summary
Ureteric obstruction occurred in 10 of 50 renal transplant patients, presenting early or late. Most cases resolved spontaneously or with surgery, with no graft loss.
Area of Science:
- Nephrology
- Urology
- Transplantation Surgery
Background:
- Renal transplantation is a critical treatment for end-stage renal disease.
- Ureteric complications can impact graft survival and patient outcomes.
Observation:
- This study reviewed 50 consecutive renal allograft recipients between September 1975 and March 1977.
- Ten patients (20%) developed ureteric obstruction, categorized by onset (early vs. late).
Findings:
- Early obstruction causes included blood clots, edema, necrosis, and compression; late obstruction was due to fibrosis.
- Two cases of edema and one of blood clot obstruction resolved spontaneously.
- Transurethral meatotomy succeeded in one patient; six required open surgery. No obstruction led to death or graft failure.
Implications:
- Ureteric obstruction is a significant complication in renal transplantation, but often manageable.
- Timely diagnosis and appropriate intervention are crucial for successful outcomes.
- This historical data provides insights into the management of ureteric complications in early renal transplant programs.