Epidemiology of intussusception in sub-Saharan Africa

Jason M Mwenda1, Jacqueline E Tate2, Umesh D Parashar2

  • 1World Health Organization (WHO) Regional Office for Africa, Brazzaville, Republic of Congo.

Insights

Intussusception surveillance in 9 countries reveals peak cases at 4-6 months. Surgical treatment and outcomes vary significantly, highlighting needs for improved diagnosis and care in sub-Saharan Africa.

Area of Science:

  • Pediatric Surgery
  • Global Health
  • Epidemiology

Background:

  • Intussusception surveillance data from nine countries were compiled.
  • The study focused on the first year of life, identifying peak incidence.
  • Surgical intervention and its associated outcomes were analyzed across diverse healthcare settings.

Discussion:

  • The age distribution of intussusception shows a clear peak between 4-6 months of age.
  • A high percentage of intussusception cases necessitate surgical intervention, often involving bowel resection.
  • Significant variability exists in treatment outcomes for intussusception across different countries.

Key Insights:

  • Intussusception predominantly affects infants aged 4-6 months.
  • Surgery is a common treatment, frequently requiring bowel resection.
  • Treatment success for intussusception varies globally.

Outlook:

  • These findings are crucial for enhancing the diagnosis and treatment of intussusception in young children.
  • The data underscore the need for standardized treatment protocols and improved surgical care in sub-Saharan Africa.
  • Further research could focus on reducing surgical complications and improving long-term outcomes for intussusception.

Related Concept Videos

Anatomy of the Intestines01:23

Anatomy of the Intestines

Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
84.2K
Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
965
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
807
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
319
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
190
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
207