Related Experiment Video
Updated: Oct 19, 2025

12:10
Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
8.1K
Rapidly recurrent prostatic obstruction due to granulomatosis with polyangiitis
Thomas Neerhut1, Gregory Neerhut2, Cleve Magree3
1Princess Alexandra Hospital, Metro South Health Brisbane, Unit 5/28 Carl Street, Woolloongabba, QLD, 4102, Australia.
Urology Case Reports
|September 23, 2021
Summary
Granulomatosis with polyangiitis (GPA) can cause granulomatous prostatitis, leading to urinary obstruction. Early diagnosis of this rare condition is crucial to avoid multiple surgeries.
Area of Science:
- Urology
- Rheumatology
- Pathology
Background:
- Granulomatous prostatitis is an uncommon condition.
- Granulomatosis with polyangiitis (GPA) is a rare systemic vasculitis.
- GPA is an infrequent cause of prostatitis.
Observation:
- A patient presented with lower urinary tract symptoms and recurrent urinary obstruction.
- The patient underwent two prostatic resections for presumed granulomatous prostatitis.
- Diagnosis of GPA was delayed, occurring after surgical interventions.
Findings:
- The case highlights granulomatous prostatitis secondary to unrecognized GPA.
- Challenges in diagnosing this rare condition are demonstrated.
- The systemic nature of GPA necessitates comprehensive patient evaluation.
Implications:
- This case underscores the importance of considering systemic diseases like GPA in unexplained prostatitis.
- Timely diagnosis of GPA can prevent unnecessary surgical procedures.
- Increased awareness among clinicians may improve patient outcomes for rare granulomatous prostatitis cases.
Related Concept Videos
Acute Kidney Injury II: Pathophysiology
248
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
248
Acute Pyelonephritis I: Introduction
95
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
95
Renal Corpuscle
3.9K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
3.9K
Glaucoma: Overview
988
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
988
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
119
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
119
Acute Pyelonephritis II: Diagnostic Studies and Management
75
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
75

