Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Plasmonic Supercavitation Enables Nanoparticle Photo-Ejection Across Air/Water Interface.

Small science·2026
Same author

Harnessing <i>C. elegans</i> as a Biosensor: Integrating Microfluidics, Image Analysis, and Machine Learning for Environmental Sensing.

Sensors (Basel, Switzerland)·2025
Same author

Ballistic Brownian motion of supercavitating nanoparticles.

Physical review. E·2021
Same author

Transitions and Instabilities in Imperfect Ion-Selective Membranes.

International journal of molecular sciences·2020
Same author

Light-Guided Surface Plasmonic Bubble Movement via Contact Line De-Pinning by In-Situ Deposited Plasmonic Nanoparticle Heating.

ACS applied materials & interfaces·2019
Same author

Overlimiting current due to electro-diffusive amplification of the second Wien effect at a cation-anion bipolar membrane junction.

Biomicrofluidics·2019

Related Experiment Video

Updated: Oct 19, 2025

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
08:06

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Published on: February 23, 2017

8.7K

Novel electroosmotic micromixer configuration based on ion-selective microsphere.

Jarrod Schiffbauer1, Georgy Ganchenko2, Nikolay Nikitin3

  • 1Department of Physical and Environmental Sciences, Colorado Mesa University, Grand Junction, CO, USA.

Electrophoresis
|September 23, 2021
PubMed
Summary

This study presents a novel micromixer design using an ion-selective microsphere. Optimal electric fields enhance mixing, but instabilities do not improve performance, revealing best mixing occurs without electrokinetic instability.

Keywords:
Ion-selective particleMicromixerNumerical modeling

More Related Videos

Microscale Vortex-assisted Electroporator for Sequential Molecular Delivery
10:51

Microscale Vortex-assisted Electroporator for Sequential Molecular Delivery

Published on: August 7, 2014

8.8K
Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.4K

Related Experiment Videos

Last Updated: Oct 19, 2025

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
08:06

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Published on: February 23, 2017

8.7K
Microscale Vortex-assisted Electroporator for Sequential Molecular Delivery
10:51

Microscale Vortex-assisted Electroporator for Sequential Molecular Delivery

Published on: August 7, 2014

8.8K
Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.4K

Area of Science:

  • Microfluidics
  • Electrokinetics
  • Computational Fluid Dynamics

Background:

  • Micromixers are crucial for efficient fluid manipulation in microfluidic devices.
  • Achieving effective mixing often requires overcoming diffusion limitations in low Reynolds number flows.
  • Electrokinetic phenomena, such as electroosmotic flow, offer tunable control over microscale fluid dynamics.

Purpose of the Study:

  • To introduce and analyze a novel micromixer configuration featuring a spherical chamber with an ion-selective microsphere.
  • To investigate the influence of external electric fields and pressure gradients on mixing efficiency.
  • To determine optimal operating conditions and explore potential instabilities for enhanced mixing.

Main Methods:

  • Direct numerical simulations were performed on a supercomputer to model fluid flow and mixing.
  • The study systematically varied electric field strength and pressure gradients.
  • Analysis focused on electroosmotic flow, pressure-driven flow, and resulting mixing patterns, including instabilities.

Main Results:

  • Optimal electric field strengths were identified for significant mixing enhancement.
  • Electrokinetic instabilities, while present, were found to confine vortices near the microsphere and not improve bulk mixing.
  • Salt concentration gradient-induced instability can enhance mixing but leads to device malfunction at high electric fields.

Conclusions:

  • The most effective mixing in this micromixer design occurs in the absence of electrokinetic instability.
  • The study provides guidelines for selecting geometric parameters for optimal mixing, achieving up to tenfold improvement over passive mixers.
  • The device shows potential for versatile applications, including electrohydrodynamic pumping and micro-reactors.