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Related Concept Videos

Bone Disorders01:29

Bone Disorders

4.3K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Fractures: Bone Repair01:27

Fractures: Bone Repair

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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
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Bone Remodeling01:40

Bone Remodeling

38.8K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Menopause01:28

Menopause

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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
2.3K
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

3.9K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

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The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
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Related Experiment Video

Updated: Oct 19, 2025

Transverse Fracture of the Mouse Femur with Stabilizing Pin
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[Update on fracture prevention after menopause].

Friederike Thomasius1, Peyman Hadji1

  • 1Frankfurter Hormon & Osteoporosezentrum, Frankfurt, Deutschland.

Therapeutische Umschau. Revue Therapeutique
|September 24, 2021
PubMed
Summary

Osteoporosis is a common, underdiagnosed condition in postmenopausal women. Gynecologists play a key role in early detection and managing long-term fracture prevention strategies, including hormone therapy.

Area of Science:

  • Gerontology
  • Endocrinology
  • Gynecology

Background:

  • Osteoporosis is a prevalent, multifactorial disease often underdiagnosed and undertreated.
  • Gynecologists are crucial in identifying women at risk during menopausal symptom onset, a period of potential accelerated bone loss.

Purpose of the Study:

  • To review current strategies for fracture prevention in postmenopausal women.
  • To emphasize the role of gynecologists in osteoporosis management and long-term patient retention.

Main Methods:

  • Review of current literature on osteoporosis and fracture prevention in postmenopausal women.
  • Discussion of the gynecologist's role as a primary point of contact for initiating bone health management.

Main Results:

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Imaging of the Microstructural Failure Mechanism in the Human Hip
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  • Accelerated bone loss and osteoporosis risk are often identified during menopause.
  • Hormone therapy is one potential treatment sequence for managing osteoporosis in this demographic.

Conclusions:

  • Early intervention and long-term management are essential for chronic conditions like osteoporosis.
  • A multidisciplinary approach involving gynecologists is vital for effective fracture prevention in postmenopausal women.