Metabolic reprogramming of glial cells as a new target for central nervous system axon regeneration
1Shriners Hospitals Pediatric Research Center, Department of Neural Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Neural Regeneration Research
|September 24, 2021
Abstract
No abstract available in PubMed .
Related Concept Videos
Neurogenesis and Regeneration of Nervous Tissue
1.2K
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
1.2K
Glial Cells
90.5K
Overview
90.5K


