Evidence for different forms of human chorionic gonadotropin receptor complex in pseudopregnant rat ovaries
Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme
|January 1, 1979
Abstract:
After in vivo application of [125 I]-iodo-hCG to pseudopregnant rats, radioactivity extracted from ovarian particulate fractions can be eluted from Sephadex G--200 columns in three various fractions (Vo, Kav = 0.15, Kav = 0.27) differing from hCG (Kav = 0.35). By lowering the pH 50% of the radioactivity is precipitated and the resuspended material shows a conversion to the smaller complexes. The supernatant material is dissociated to [125I]-iodo-hCG. In alkaline milieu [125I]-iodo-HCG is dissociated completely from the complexes.
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