Related Experiment Video
Updated: Oct 19, 2025

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
Published on: November 3, 2023
Does shock index, pediatric age-adjusted predict mortality by trauma center type?
John R Austin1, Chaonan Ye, Moon O Lee
1From the Division of Pediatric Surgery, Department of Surgery (J.R.A., C.Y., S.D.C.) and Department of Emergency Medicine (M.O.L.), Stanford University School of Medicine, Stanford, California.
Pediatric trauma patients with elevated shock index, pediatric age-adjusted (SIPA) showed no difference in mortality across adult, mixed, or pediatric trauma centers. However, other factors suggest specialized care may optimize outcomes.
Area of Science:
- Trauma Surgery
- Pediatric Critical Care
- Health Services Research
Background:
- Pediatric trauma patients are treated in diverse settings: adult trauma centers (ATCs), mixed pediatric and ATCs (MTCs), and pediatric trauma centers (PTCs).
- The shock index, pediatric age-adjusted (SIPA) is a tool to identify severely injured children.
- Understanding outcomes based on trauma center type for high-risk pediatric patients is crucial.
Purpose of the Study:
- To compare mortality and hospital length of stay (LOS) among pediatric trauma patients with elevated SIPA (eSIPA) treated at ATCs, MTCs, and PTCs.
- To analyze secondary outcomes including splenectomy, CT chest scans, and laparotomy rates across different trauma center types.
Main Methods:
- A retrospective analysis of the 2013-2016 National Trauma Data Bank included pediatric patients (1-14 years) with eSIPA.
- Multivariable regression analyses were performed to compare outcomes, controlling for patient and hospital factors.
- Statistical significance was determined using an alpha level of 0.01.
Main Results:
- No significant difference in mortality was found among eSIPA patients across ATCs, MTCs, and PTCs, even for those with severe injuries (Injury Severity Score > 25).
- Splenectomy and computed tomography (CT) chest scan rates were significantly higher at ATCs and MTCs compared to PTCs.
- Laparotomy rates and hospital LOS did not differ significantly between trauma center types.
Conclusions:
- Elevated SIPA in pediatric trauma patients does not correlate with differential mortality based on trauma center type.
- Higher rates of specific interventions (splenectomy, CT chest scans) at ATCs and MTCs suggest potential differences in care patterns.
- Pediatric trauma centers may offer optimized care, warranting further investigation into specialized pediatric trauma management.
Related Concept Videos
Drug Dosing: Infants and Children
Blood Pressure Imbalances and Circulatory Shock
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...

