Related Experiment Video
Updated: Oct 19, 2025

Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
Published on: May 6, 2020
Imaging in Osteoarthritis
F W Roemer1, A Guermazi2, S Demehri3
1Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, FGH Building, 3rd Floor, 820 Harrison Ave, Boston, MA, 02118, USA; Department of Radiology, Friedrich-Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Maximiliansplatz 3, Erlangen, 91054, Germany.
Osteoarthritis (OA) imaging is advancing rapidly, with magnetic resonance imaging (MRI) as a key tool. This review covers various OA imaging techniques for researchers and clinicians.
Area of Science:
- Orthopedics
- Radiology
- Biomedical Engineering
Background:
- Osteoarthritis (OA) is a prevalent degenerative joint disease with significant health and economic impacts.
- Joint imaging, especially MRI, has seen rapid advancements, crucial for clinical research in OA.
- Understanding OA imaging is vital for scientists, clinicians, and industry professionals interested in the condition.
Purpose of the Study:
- To provide a comprehensive introduction to various Osteoarthritis (OA) imaging modalities.
- To discuss the current role and advancements in radiography and joint space width measurement.
- To review cartilage morphology and biochemical composition assessment techniques in OA research.
Main Methods:
- Narrative review of existing literature on OA imaging techniques.
- Discussion of radiography, ultrasound, computed tomography (CT), and metabolic imaging.
- Focus on magnetic resonance imaging (MRI) advancements for OA assessment.
Main Results:
- Radiography remains important, with progress in joint space width measurement.
- MRI is the primary imaging method in OA research, offering detailed cartilage assessment.
- Quantitative 3D morphologic and semi-quantitative whole-organ OA assessments are advancing.
Conclusions:
- Magnetic resonance imaging (MRI) is the leading modality for Osteoarthritis (OA) research.
- Other imaging techniques like ultrasound and CT provide complementary information.
- Continued advancements in imaging are essential for better OA understanding and management.
Related Concept Videos
Ultrasonography
During an ultrasonography procedure, a handheld device called...
Imaging Studies III: Computed Tomography
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies VII: Vascular Imaging
X-ray Imaging

