Related Experiment Video
Updated: Oct 19, 2025

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
Published on: March 26, 2018
Aortic valve replacement in a patient with self-reported systemic multiple metal allergy
Saori Nagura1, Mari Sakai2, Hayato Obi2
1Department of Cardiovascular Surgery, Minaminagano Medical Center, Shinonoi General Hospital, 666-1, Shinonoi-Ai, Nagano, 388-8004, Japan. saori790925@gmail.com.
A 74-year-old man with severe aortic stenosis and systemic metal allergy underwent successful aortic valve replacement. The metal-free Avalus bioprosthetic valve proved highly effective for this patient.
Area of Science:
- Cardiovascular Surgery
- Allergy and Immunology
- Biomaterials Science
Background:
- Severe aortic stenosis necessitates valve replacement.
- Systemic metal allergy presents a significant challenge for implantable device selection.
- Traditional bioprosthetic valves may contain metal components, posing risks for allergic patients.
Observation:
- A 74-year-old male patient presented with severe aortic stenosis.
- The patient had a history of palmoplantar pustulosis and diagnosed systemic metal allergy.
- Standard treatment options were limited due to metal hypersensitivity.
Findings:
- Aortic valve replacement was performed using the Avalus bioprosthetic valve.
- The Avalus valve features a metal-free stent design.
- The patient tolerated the procedure and implant well, with no signs of allergic reaction.
Implications:
- The Avalus bioprosthetic valve offers a safe and effective alternative for aortic valve replacement in patients with metal allergies.
- This case highlights the importance of considering patient-specific allergies in device selection for cardiac surgery.
- Further research into metal-free cardiovascular implants is warranted to expand treatment options.
More Related Videos
05:31Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
12:17Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Related Concept Videos
Aortic Regurgitation III: Medical Management
Mitral Stenosis III: Medical Management
Rheumatic Heart Disease III: Medical Management
Mitral Stenosis IV: Nursing Management
Mitral Valve Prolapse II: Assessment and Management
Aortic Regurgitation IV: Nursing Management