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Immunosensing Based on Optical Fiber Technology: Recent Advances.

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This summary is machine-generated.

Optical fiber immunosensors offer versatile biosensing by leveraging evanescent wave (EW) or plasmonic methods like surface plasmon resonance (SPR). This review covers configurations, strategies, and future trends for these advanced optical sensors.

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antibodybiofunctionalizationbiosensoroptical fibersurface plasmon resonance (SPR)

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Area of Science:

  • Optoelectronics and Photonics
  • Biomedical Engineering
  • Chemical Sensing

Background:

  • Optical fiber technology has transformed various fields due to its unique properties.
  • Optical fiber biosensors detect analytes by exposing guided light to surrounding media.
  • Biosensing configurations vary in complexity, cost, and performance.

Purpose of the Study:

  • To provide a comprehensive overview of optical fiber immunosensors for a broad audience.
  • To highlight recent research trends and advancements in optical fiber biosensing.
  • To discuss practical applications and future directions in the field.

Main Methods:

  • Review of different optical fiber configurations (uncladded, U-shape, D-shape, tapered, gratings, etc.).
  • Explanation of biofunctionalization strategies: evanescent wave (EW) and plasmonic methods (SPR, LSPR).
  • Analysis of light-analyte interactions at the fiber-media interface.

Main Results:

  • Detailed examination of various optical fiber configurations and their suitability for biosensing.
  • Comparison of EW, SPR, and LSPR techniques for analyte detection.
  • Presentation of practical application examples across different domains.

Conclusions:

  • Optical fiber immunosensors are a powerful tool for diverse biosensing applications.
  • Advancements in configurations and biofunctionalization strategies continue to enhance sensor performance.
  • The field presents significant challenges but offers a promising outlook for future innovations.