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Updated: Oct 19, 2025

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
[Melanoma: A pediatric challenge. A two cases report]
Tatiana Bendersky1, Daniela Berlingieri2, Sonia Rojas2
1Clínica Pediátrica. Hospital de Niños Ricardo Gutiérrez, Ciudad Autónoma de Buenos Aires, Argentina. tatianabendersky@gmail.com.
Abstract:
Melanoma is the most serious skin cancer. Morbimortality is variable as it is related to the preventive measures, early detection, and access to early treatment. The incidence has increased in recent years, despite the raise in awareness of avoiding sun exposure and the use of sunscreen. What is more, the disease age range has expanded, affecting increasingly younger individuals. It is estimated that 1 to 4 % of all melanoma cases occurred in people younger than twenty years old. We present two pediatric cases with prolonged evolution and wrong initial diagnosis. Since the general pediatrician is the patient's first contact with the health system, it is extremely important to know the characteristics of these lesions. A high index of suspicion would allow an early referral to the specialist.

