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Intracoronary Thrombogenicity in Patients with Vasospastic Angina: An Observation Using Coronary Angioscopy

Hiroki Teragawa1, Yuichi Orita1, Chikage Oshita1

  • 1Department of Cardiovascular Medicine, JR Hiroshima Hospital, 3-1-36 Futabanosato, Higashi-ku, Hiroshima 732-0057, Japan.

Diagnostics (Basel, Switzerland)
|September 28, 2021
PubMed

Insights

Intracoronary thrombi were found in 30% of patients with vasospastic angina (VSA). Atherosclerotic changes and spasms in coronary arteries are significant factors contributing to thrombus formation in VSA patients.

Area of Science:

  • Cardiology
  • Vascular Biology

Background:

  • Intracoronary thrombi in vasospastic angina (VSA) lack clear understanding.
  • Investigating the link between VSA and intracoronary thrombi is crucial.

Purpose of the Study:

  • To investigate the relationship between VSA and intracoronary thrombi.
  • To identify clinical and lesional characteristics associated with thrombus formation in VSA.

Main Methods:

  • Retrospective study of 60 VSA patients assessed with coronary angioscopy (CAS).
  • Defined intracoronary thrombi as white or erosion-like red thrombi on CAS.
  • Analyzed clinical and lesional characteristics for thrombus risk factors.

Main Results:

  • Intracoronary thrombi were present in 18 (30%) VSA patients.
  • Atherosclerotic changes and segmental spasms were significant factors for thrombus formation.
  • No statistically significant difference in clinical factors (male, smoking, symptoms) upon logistic regression.

Conclusions:

  • Intracoronary thrombi occur in 30% of VSA patients.
  • Highlights the importance of intracoronary thrombogenicity in VSA.
  • Further attention is needed for VSA patients prone to thrombus formation.
Abstract

Keywords:
angioscopycoronary erosioncoronary spasmvasospastic angina

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