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Novel Photonic Bio-Chip Sensor Based on Strained Graphene Sheets for Blood Cell Sorting
Fatemeh Ghasemi1, Sepehr Razi2
1Laser Center, Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
Molecules (Basel, Switzerland)
|September 28, 2021
Summary
This study introduces a tunable photonic biochip for blood cell sorting. The novel design utilizes multi-layered materials and graphene coatings to effectively differentiate between white and red blood cells based on their optical properties.
Area of Science:
- Photonics
- Biomedical Engineering
- Materials Science
Background:
- Accurate blood cell sorting is crucial for diagnostics and research.
- Existing methods may lack sensitivity or tunability for specific cell types.
Purpose of the Study:
- To propose and analyze a novel tunable photonic biochip for blood cell sorting.
- To investigate the chip's sensitivity and detectivity for distinguishing blood components.
Main Methods:
- Design of a multi-layered biochip using ZnS and Ge slabs with encapsulated air slabs.
- Incorporation of graphene sheets on bio-cell walls to enhance sensitivity.
- Optimization of structural parameters and exploration of tunability via incident light angle, polarization, and graphene strain.
Main Results:
- The biochip demonstrates effective identification of selected blood components (white and red blood cells).
- Distinct optical features induced by different cell types were observed.
- Varied figures of merit and sensitivity levels were recorded for different blood components.
Conclusions:
- The proposed photonic biochip offers a tunable and sensitive platform for blood cell sorting.
- The design allows for effective differentiation of blood components based on optical characteristics.
