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Author Spotlight: Advancing Thymic Epithelial Cells and T-Cell Research with Human Thymic Organoids
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Thymic endocrinology Part-1

Arundhati Dasgupta1, Sanjay Kalra2

  • 1Department of Endocrinology, Rudraksh Clinic, Siliguri, India.

JPMA. the Journal of the Pakistan Medical Association
|September 28, 2021
PubMed

The concept of thymic endocrinology describes a bidirectional effect: the thymic hormones which circulate and significantly affect the immunomodulatory function of the body and the action of the other hormones derived from the pituitary, adrenal, gonads and thyroid gland on the thymocytes, thymic epithelial cells and the thymic stromal cells. Apart from this there is also an extensive paracrine and autocrine endocrine signal network within the Intra-thymic environment involving interleukins and thymic peptides. This review attempts to delve into the understanding of this intrinsic relationship between the thymus gland and the endocrine system at large.

Keywords:
Thymic endocrinology, Bidirectional effect, Immunomodulatory function.

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