Related Experiment Video
Updated: Oct 18, 2025

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
Published on: March 8, 2019
All soft contact lenses are not created equal.
Nathan Efron1, Philip B Morgan2, Jason J Nichols3
1School of Optometry and Vision Science, Queensland University of Technology, Kelvin Grove, Queensland, Australia.
Substituting prescribed soft contact lenses can lead to patient dissatisfaction and adverse ocular events. All soft contact lenses are not created equal and require proper fitting, not substitution.
Area of Science:
- Ophthalmology
- Optometry
- Biomaterials Science
Background:
- Soft contact lenses are medical devices prescribed by eye care practitioners.
- Substitution of prescribed lenses by suppliers occurs due to a misconception of interchangeability.
- This practice can have significant implications for ocular health and patient satisfaction.
Purpose of the Study:
- To review the implications of inappropriate soft contact lens substitution.
- To identify potential patient dissatisfaction and adverse events linked to lens property and usage variations.
- To emphasize the importance of adhering to prescriptions for contact lens fitting.
Main Methods:
- Literature review examining lens properties and usage parameters.
- Analysis of potential consequences arising from the substitution of 16 different soft contact lens properties and usage factors.
- Consideration of patient-reported outcomes and adverse ocular events.
Main Results:
- Substitution of 15 out of 16 considered lens properties (excluding back surface design) was linked to adverse outcomes.
- These outcomes included patient dissatisfaction and ocular events, ranging from one to six potential sources per property.
- Specific properties like surface treatment, material, and wearing modality significantly impact lens performance and safety.
Conclusions:
- Soft contact lenses are not interchangeable and require professional prescription and fitting.
- Lens substitution can lead to compromised vision, ocular health issues, discomfort, and cosmetic concerns.
- Adherence to prescribed lens types and usage is crucial for patient safety and satisfaction.
Related Concept Videos
Focusing of Light in the Eye
Pharmaceutical Alternatives: Polymorphic Form-Related and Particle Size-Related Therapeutic Nonequivalence
Angle Closure Glaucoma: Treatment
Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Pharmaceutical Equivalents

