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Updated: Oct 18, 2025

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A new cyclopentenone derivative from Trichoderma atroviride HH-01
Li Zhu1, Jia-Peng Wang1, Feng Hao1
1Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan, Province, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, P.R. China.
Abstract:
A new cyclopentenone derivative, atrovinol (1), together with ten known compounds (2-11) were isolated from Trichoderma atroviride HH-01, an endophytic fungus from Illigera rhodantha (Hernandiaceae). Their structures were identified by HRESIMS, 1 D/2D NMR, and electronic circular dichroism (ECD) spectra. Compound 1 exhibited moderate inhibitory activity against Staphylococcus aureus and Bacillus subtilis with MIC values of 8.0 µg/mL and 16.0 µg/mL, respectively.
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