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Updated: Oct 18, 2025

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
[Management of cardiogenic shock: a proposal for a shared protocol]
Stefano Benenati1, Matteo Vercellino2, Davide Avenoso1
1Cattedra di Malattie Cardiovascolari, Dipartimento di Medicina Interna (DIMI), Università degli Studi, Genova.
Insights
A new protocol for managing cardiogenic shock (CS) was implemented in 2019. This multidisciplinary approach aims to improve patient outcomes and resource allocation through standardized care and mechanical support device utilization.
Area of Science:
- Cardiology
- Critical Care Medicine
Background:
- Cardiogenic shock (CS) is a severe condition with high mortality rates.
- Optimal management requires comprehensive hemodynamic assessment and goal-directed therapy.
- Mechanical support devices offer hemodynamic sustainment with fewer cardiotoxic effects than traditional therapies.
Purpose of the Study:
- To introduce and evaluate a new multidisciplinary protocol for cardiogenic shock management.
- To streamline patient care, enhance specialist cooperation, and optimize resource allocation.
- To address mechanical support device implantation and palliative care referral in CS patients.
Main Methods:
- Implementation of a novel, multidisciplinary CS management protocol in 2019.
- Focus on pre-established, shared protocols for consistent care delivery.
- Integration of comprehensive hemodynamic monitoring and tailored medical therapy.
- Consideration of mechanical circulatory support devices and palliative care referral.
Main Results:
- The protocol aims to improve prognosis and resource allocation for high-risk CS patients.
- Enhanced cooperation among healthcare specialists is a key objective.
- Streamlined management addresses critical issues like mechanical support and palliative care.
Conclusions:
- A structured, multidisciplinary approach to cardiogenic shock can improve patient outcomes.
- The adopted protocol standardizes care, optimizes interventions, and facilitates critical decision-making.
- This protocol represents a significant step in managing complex CS cases, aligning with international best practices.
Abstract:
Cardiogenic shock (CS) is a complex and relatively rare disease. Whilst its mortality remains unacceptably high, a multidisciplinary approach based on pre-established and shared protocols may improve prognosis and ensure appropriate resource allocation. Comprehensive hemodynamic assessment and monitoring as well as tailored, goal-directed medical therapy are part of an optimal management. Moreover, mechanical support devices may be helpful as they sustain hemodynamics to a greater extent as compared to inotropes and vasopressors, while lacking their cardiotoxic effects. Therefore, they are increasingly used in CS patients. In 2019, a new protocol for the management of patients with CS was adopted at the Ospedale Policlinico San Martino (HSM) in Genoa, Italy. Following in the footsteps of similar international experiences, the HSM protocol aims at streamlining the management of these high-risk patients improving the cooperation among healthcare specialists, and also addressing the key issues of mechanical support device implantation and appropriate referral for palliative care.
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