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Updated: Oct 18, 2025

An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
[SCORE2 - an updated model for cardiovascular risk prediction].
Mattias Brunström1, Jonas Andersson2, Mats Eliasson3
1med dr, ST-läkare, Hjärtcentrum, Norrlands universitetssjukhus, Umeå.
The updated SCORE2 model provides more accurate cardiovascular disease risk prediction in Sweden than the older SCORE model. This new model aids in primary prevention strategies by assessing both disease incidence and mortality risk.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Cardiovascular disease (CVD) is the leading cause of death and lost life-years in Sweden.
- Accurate CVD risk prediction is crucial for effective primary prevention strategies.
- The Systematic COronary Risk Evaluation (SCORE) model has been the standard in Sweden for nearly 20 years.
Purpose of the Study:
- To introduce and report the SCORE2 risk prediction model for the Swedish population.
- To provide updated cardiovascular risk charts tailored for Sweden, classified as a moderate-risk country.
- To address limitations of the previous SCORE model by incorporating contemporary data and competing risks.
Main Methods:
- Utilized contemporary data to develop the SCORE2 model.
- Included prediction of incident cardiovascular disease alongside cardiovascular mortality.
- Accounted for competing risks in the risk assessment framework.
- Translated the SCORE2 risk charts for moderate-risk countries into Swedish.
Main Results:
- Sweden is classified as a moderate-risk country under the SCORE2 model.
- The SCORE2 model offers a more comprehensive risk assessment than the previous SCORE model.
- The study reports the specific risk charts for moderate-risk countries adapted for Swedish use.
Conclusions:
- The SCORE2 model represents a significant advancement in cardiovascular risk prediction for Sweden.
- Updated risk stratification using SCORE2 can enhance the precision of primary prevention interventions.
- The availability of Swedish-translated SCORE2 charts facilitates clinical application in primary care settings.
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