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Multifocal Pattern Dystrophy Simulating Fundus Flavimaculatus: Multimodal Imaging for Early Diagnosis.
Tryfon Rotsos1, Alexandra Gkounta2, Chrysanthos Symeonidis3
11st Department of Ophthalmology, University of Athens, Athens, Greece.
Case Reports in Ophthalmology
|October 1, 2021
Summary
Multifocal pattern dystrophy simulating fundus flavimaculatus (MPDSFF) presents with vision changes but often maintains good visual acuity (VA) despite anatomical changes. Slow progression is typical, with significant VA loss potentially linked to choroidal neovascularization.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Medical Imaging
Background:
- Multifocal pattern dystrophy simulating fundus flavimaculatus (MPDSFF) is a rare retinal condition.
- Diagnosis relies on a combination of clinical examination and advanced imaging techniques.
Observation:
- A case study of a 58-year-old female with MPDSFF presenting with bilateral floaters and metamorphopsia.
- Initial best-corrected visual acuity was 6/6 in both eyes.
- Optical coherence tomography (OCT) showed initial progression within 6 months, stabilizing over the subsequent 12 months.
Findings:
- Clinical and imaging findings confirmed MPDSFF.
- Despite anatomical changes on OCT, visual prognosis remained relatively good.
- Disease progression was slow, with potential VA reduction secondary to choroidal neovascularization.
Implications:
- Regular follow-up with OCT, pattern electroretinogram (PERG), and autofluorescence (AF) is crucial for MPDSFF patients.
- Limited literature necessitates further research into cellular death pathways for potential therapeutic strategies.
- Early identification and monitoring can help manage MPDSFF and preserve visual function.

