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Pneumatic Retinopexy for the Management of Rhegmatogenous Retinal Detachment.
Konstantinos Zinovios1,2, Sofia Androudi3,2, Athanasios Karamitsos4,2
1First Ophthalmology Department, Ophthalmiatreio Athinon, Athens, GRC.
Cureus
|November 17, 2025
Summary
Pneumatic retinopexy (PnR) offers better visual outcomes and fewer cataracts than pars plana vitrectomy (PPV) for retinal detachment. While PnR has a lower initial success rate, final attachment rates are similar, making it a preferred choice for visual function.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Minimally Invasive Procedures
Background:
- Rhegmatogenous retinal detachment (RRD) requires surgical intervention.
- Pars plana vitrectomy (PPV) is a common but invasive RRD repair method.
- Pneumatic retinopexy (PnR) is a less invasive, office-based alternative for select RRD cases.
Purpose of the Study:
- To compare the functional outcomes and complication rates of Pneumatic Retinopexy (PnR) versus Pars Plana Vitrectomy (PPV) for RRD repair.
- To elucidate the reasons behind the observed differences in visual acuity and cataract progression between PnR and PPV.
- To provide evidence-based insights for selecting the optimal surgical technique for RRD management.
Main Methods:
- Literature search of PubMed, Cochrane Library, and Google Scholar for comparative studies of PnR and PPV.
- Inclusion of systematic reviews, meta-analyses, and randomized controlled trials (RCTs) published in English within the last 10 years.
- Narrative review synthesizing findings on visual outcomes, metamorphopsia, and cataract development.
Main Results:
- PnR demonstrates superior best-corrected visual acuity (BCVA) and reduced metamorphopsia compared to PPV.
- PnR is associated with significantly lower rates of cataract progression than PPV.
- While primary PnR reattachment rates are lower, final anatomical success rates are comparable to PPV.
- Reduced retinal displacement and preserved photoreceptor integrity contribute to better visual outcomes with PnR.
Conclusions:
- PnR provides superior functional visual outcomes and a lower risk of cataract progression compared to PPV for RRD repair.
- The choice between PnR and PPV should consider not only anatomical success but also the quality of vision.
- Further large-scale RCTs with extended follow-up are warranted to confirm these findings and focus on visual quality metrics.

