Related Experiment Video
Updated: Oct 18, 2025

Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples
Published on: April 21, 2014
Septal Ablation Versus Surgical Myomectomy for Hypertrophic Obstructive Cardiomyopathy
F Pelliccia1, H Seggewiss2, F Cecchi3
1Department of Cardiovascular Sciences, University Sapienza, Via del Policlinico 155, 00161, Rome, Italy. f.pelliccia@mclink.it.
Choosing between surgical myectomy and alcohol septal ablation for hypertrophic cardiomyopathy (HCM) with left ventricular outflow tract obstruction (LVOTO) remains challenging. A multidisciplinary HCM heart team approach is emerging to optimize patient care and treatment selection.
Area of Science:
- Cardiology
- Cardiovascular Surgery
Background:
- Hypertrophic cardiomyopathy (HCM) with left ventricular outflow tract obstruction (LVOTO) causes significant symptoms and functional decline.
- Surgical myectomy and alcohol septal ablation (ASA) are invasive options for relieving LVOTO.
- Optimal treatment selection for individual HCM patients with LVOTO remains a clinical challenge.
Purpose of the Study:
- To review current invasive strategies for managing LVOTO in HCM.
- To discuss the challenges and emerging concepts in treatment selection for HCM patients.
- To highlight the importance of a multidisciplinary approach in HCM management.
Main Methods:
- Review of recent guidelines and retrospective studies on HCM treatment.
- Analysis of expert opinions regarding invasive interventions for LVOTO.
- Discussion of the evolving role of the "HCM heart team".
Main Results:
- Invasive strategies for LVOTO in HCM are now included in international guidelines.
- Management decisions are influenced by local expertise and patient preference.
- A collaborative "HCM heart team" approach is gaining traction.
Conclusions:
- Effective management of HCM with LVOTO requires a multidisciplinary team.
- The "HCM heart team" concept is crucial for navigating treatment complexities.
- Standardizing the choice of intervention based on individual patient profiles is an ongoing area of focus.
More Related Videos
07:02Operating Transverse Aortic Constriction with Absorbable Suture to Obtain Transient Myocardial Hypertrophy
Published on: September 9, 2020
08:42Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiomyopathy V: Interprofessional Care
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy IV: Restrictive Cardiomyopathy
Mitral Stenosis III: Medical Management
Cardiomyopathy II: Dilated Cardiomyopathy