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Updated: Oct 18, 2025

Ultrafast Lignin Extraction from Unusual Mediterranean Lignocellulosic Residues
Published on: March 9, 2021
Rapid and efficient microwave-assisted guanidine hydrochloride deep eutectic solvent pretreatment for biological
Lei Zhong1, Chao Wang1, Guihua Yang1
1State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan, Shandong 250353, China.
Abstract:
Microwave-assisted guanidine hydrochloride deep eutectic solvents (DESs) was developed for rapid and efficient pretreatment of castor stalk. The DES synthesized with guanidine hydrochloride and lactic acid showed a better delignification (92.02%) and enzymatic saccharification yield (96.3%) than choline chloride and lactic acid DES resulted. In addition, high-purity (up to 98%) lignin was recovered from the pretreatment liquor. The good recyclability of the guanidine hydrochloride-based DES was also proven with up to 90% cellulose hydrolysis with third-time recycled DES without post purification. The proposed microwave-assisted guanidine hydrochloride/lactic acid DES showed its great potentials as a highly effective and recyclable pretreatment solvent for future biorefinery strategies.
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