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The braingraph.org database with more than 1000 robust human connectomes in five resolutions
Bálint Varga1, Vince Grolmusz1,2
1PIT Bioinformatics Group, Eötvös University, 1117 Budapest, Hungary.
Cognitive Neurodynamics
|October 4, 2021
Summary
This study releases 5320 human brain connectomes derived from MRI data, offering multi-resolution brain graph datasets for researchers. These connectomes facilitate the study of human brain connectivity across various scientific disciplines.
Area of Science:
- Neuroscience
- Computational Biology
- Data Science
Background:
- Mapping human brain connectivity at the neuronal level is currently infeasible.
- Magnetic Resonance Imaging (MRI) enables macroscopic connection mapping between brain areas.
- Neuroimaging workflows involve complex steps prone to errors.
Purpose of the Study:
- To publish a comprehensive dataset of human connectomes.
- To provide multi-resolution brain graph data for broader scientific access.
- To facilitate interdisciplinary research in human brain connectivity.
Main Methods:
- Utilized public Human Connectome Project MRI data.
- Computed 1064 human connectomes across 5 resolutions (83 to 1015 nodes).
- Implemented an averaging and extreme value deletion strategy for error correction.
Main Results:
- Published 1064 human connectomes, resulting in 5320 downloadable braingraphs.
- Data available in 5 distinct resolutions with anatomically labeled nodes.
- Ensured data quality through rigorous error correction strategies.
Conclusions:
- The released dataset provides accessible, multi-resolution human brain connectomes.
- Enables researchers from diverse fields (mathematics, physics, engineering) to analyze brain connectivity.
- Supports robust connectomical studies for neuroscientists and computational neuroscientists.
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