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Grossing of Non-neoplastic Globes, Including Fetal Eyes
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Pregnancy and the eye.

Edmund W C Khong1,2, Helen H L Chan3,4, Stephanie L Watson5,6

  • 1Department of Surgery, Central Clinical School, Monash University.

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|October 4, 2021
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Summary
This summary is machine-generated.

Pregnancy can cause eye changes and affect conditions like glaucoma and diabetic retinopathy. Optimal treatment during pregnancy remains uncertain, necessitating further research and collaborative care.

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Area of Science:

  • Ophthalmology
  • Maternal-Fetal Medicine
  • Public Health

Background:

  • Pregnancy is associated with various physiological changes that can impact ocular health.
  • Preexisting eye conditions require careful management during pregnancy due to potential risks to both mother and fetus.

Purpose of the Study:

  • To review common ocular changes during pregnancy.
  • To examine the effects of pregnancy on pre-existing conditions like glaucoma and diabetic retinopathy.
  • To highlight treatment challenges for eye conditions during pregnancy.

Main Methods:

  • Literature review of studies on pregnancy and ocular conditions.
  • Analysis of current treatment guidelines and safety data.
  • Synthesis of information on refractive changes, glaucoma, diabetic retinopathy, and uveitis.

Main Results:

  • Refractive changes, particularly in keratoconus, may persist postpartum.
  • Glaucoma treatment safety in pregnancy is largely unknown; selective laser trabeculoplasty is preferred.
  • Anti-VEGF agents for diabetic retinopathy should be avoided in early pregnancy due to unknown fetal effects.
  • Noninfectious uveitis often improves during pregnancy, allowing for reduced systemic therapy.

Conclusions:

  • Ocular changes during pregnancy necessitate further research for clear treatment recommendations.
  • Balancing maternal sight preservation and fetal health is crucial.
  • Preconception planning and multidisciplinary care are essential for managing eye conditions in pregnant patients.