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Bones of the Upper Limb: Radius

Bones of the Upper Limb: Radius

The radius is longer of the two bones that make up the human antebrachium or forearm. At the proximal end, the radius articulates with the capitulum of the humerus and the radial notch of the ulna to form the elbow joint. At the distal end, the radius articulates with the ulna via the ulnar notch, forming the distal radioulnar joint. Distally, the radius also attaches to the carpal wrist bones (scaphoid and lunate) to form the radiocarpal joint.
The radius has a nail-shaped head, and a...

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A Syngeneic Orthotopic Osteosarcoma Sprague Dawley Rat Model with Amputation to Control Metastasis Rate

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Invasive Tendon Sheath Fibrosarcoma Causing Radial Osteolysis in a Golden Retriever.

Mary Coleman, Matthew R Cook, Roy R Pool

Journal of the American Animal Hospital Association

|October 4, 2021

Summary

This summary is machine-generated.

A rare tendon sheath malignancy was identified in a golden retriever presenting with limb lameness. This fibrosarcoma, initially misdiagnosed, highlights the importance of thorough histopathology for accurate cancer diagnosis in dogs.

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Area of Science:

Veterinary Pathology
Canine Oncology
Soft Tissue Sarcomas

Background:

A golden retriever presented with progressive lameness and radiographic evidence of a destructive lesion in the distal radius.
Initial fine-needle aspirate cytology suggested sarcoma, with osteosarcoma as the primary differential diagnosis.

Observation:

Post-amputation histopathology revealed a fibrosarcoma originating from an extensor tendon sheath, with secondary invasion into the radius.
Key findings included a lack of osteoid deposition, differentiating it from typical osteosarcoma.

Findings:

The case describes a previously undocumented malignancy of the tendon sheath in a canine patient.
Histopathological re-evaluation confirmed fibrosarcoma, emphasizing its origin in the tendon sheath and subsequent bone invasion.

Implications:

This case highlights the importance of considering rare tumor origins and the necessity of comprehensive histopathological examination for accurate diagnosis.
Early and accurate diagnosis of such rare canine malignancies can lead to improved patient outcomes, as demonstrated by the dog's long-term recovery.