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Updated: Oct 17, 2025

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Deep learning for predicting uncorrected refractive error using posterior segment optical coherence tomography

Tae Keun Yoo1,2,3, Ik Hee Ryu4,5, Jin Kuk Kim4,5

  • 1B&VIIT Eye Center, Seoul, South Korea. eyetaekeunyoo@gmail.com.

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Summary
This summary is machine-generated.

A deep learning model uses optical coherence tomography (OCT) images to estimate refractive error, showing potential for clinical use in detecting high myopia and preventing overlooked risks.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Refractive error estimation is crucial for eye health.
  • Current methods may not always capture subtle changes.
  • Optical coherence tomography (OCT) offers detailed posterior segment imaging.

Purpose of the Study:

  • To evaluate a deep learning model for estimating uncorrected refractive error.
  • To assess the model's ability to detect high myopia using OCT images.
  • To explore the potential of OCT as an imaging modality for refractive error assessment.

Main Methods:

  • A retrospective study with development and test datasets.
  • A deep learning regression model (ResNet50) trained on horizontal OCT images to predict spherical equivalent (SE).
  • Evaluation of the model for high myopia detection and visualization of features using saliency maps (Grad-CAM).

Main Results:

  • The model achieved a low mean absolute error (2.66 D) for SE prediction.
  • A significant Pearson correlation coefficient (0.588) was observed in the test dataset.
  • The model demonstrated an area under the ROC curve of 0.813 for high myopia detection with 71.4% accuracy.

Conclusions:

  • Deep learning algorithms can estimate refractive error from OCT images.
  • This approach may aid clinicians in identifying refractive error risks during OCT assessments.
  • OCT shows promise as an imaging modality for refractive error evaluation.