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Updated: Aug 1, 2026

Isolation of Neonatal Extrahepatic Cholangiocytes
Published on: June 5, 2014
Neonatal biliary atresia combined with preduodenal portal vein: A case report
Xian-Lan Xiang1, Peng Cai1, Jun-Gang Zhao1
1Department of Pediatric Surgery, Children's Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China.
Background:
Congenital biliary atresia is a type of obstruction of the bile ducts inside and outside the liver, which can lead to cholestatic liver cirrhosis and eventually liver failure. The preduodenal portal vein (PD-PV) is a rare developmental malformation of the PV. The PV courses in front of the duodenum. However, very few cases of neonatal biliary atresia combined with PD-PV have been reported in the scientific literature.
Case Summary:
A 1-mo-and-4-d-old child was admitted to the hospital in January because of yellowish skin. After surgical consultation, surgical intervention was recommended. The child underwent Hilar-jejunal anastomosis, duodenal rhomboid anastomosis, and abdominal drainage under general anesthesia. During the operation, the PV was located at the anterior edge of the duodenum.
Conclusion:
Diagnoses: (1) Congenital biliary atresia; (2) PD-PV; and (3) Congenital cardiovascular malformations. Outcomes: Recommendation for liver transplantation. Lessons: The choice of treatment options for neonatal biliary atresia combined with PD-PV.

