[The antibiotic galtamycin. Its fermentation, isolation, physicochemical and biological properties]

A culture of Streptomyces sp., producing an antibiotic named galtamycin was isolated from a soil sample collected in the Gorno-Altai Autonomous Region. The antibiotic belongs to anthracyclines. Biosynthesis, isolation, physico-chemical and biological properties of the antibiotic are described. The studies showed that galtamycin consisting of a chromophore and three unidentified sugars is a new compound differing from the known anthracyclines except trypanomycin by the absence of the UV absorption maximum at 230-240 nm. Galtamycin differs from trypanomycin by the molecular weight of the chromophore. Galtamycin showed low antitumor activity and was inactive against grampositive and gramnegative organisms and fungi.