Related Experiment Video
Updated: Oct 17, 2025

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024
The Missed Value of Underutilizing Pediatric Epilepsy Surgery: A Systematic Review
Christopher W Beatty1, Jason P Lockrow2, Satyanarayana Gedela3
1The Ohio State University and Nationwide Children's Hospital, Division of Neurology, Department of Pediatrics, Columbus, OH.
Insights
Pediatric epilepsy surgery is underutilized, despite its long-term benefits. Addressing family, provider, and system-level barriers can improve access to this vital treatment for children with drug-resistant epilepsy (DRE).
Area of Science:
- Neurology
- Pediatric Medicine
- Health Services Research
Background:
- Pediatric epilepsy surgery remains significantly underutilized, with only 1%-11% of children with drug-resistant epilepsy (DRE) receiving surgical treatment.
- Less than half of pediatric epilepsy patients who could benefit from surgery actually undergo the procedure.
Purpose of the Study:
- To systematically review factors contributing to the underutilization of pediatric epilepsy surgery.
- To evaluate the impact of underutilization on individual patients and the healthcare system.
Main Methods:
- A systematic review of articles was conducted using major scientific databases: PubMed, EMBASE, and Web of Science.
- The review focused on identifying factors associated with surgery underutilization and its consequences.
Main Results:
- Key factors contributing to underutilization include family misconceptions, insufficient provider knowledge, and systemic health disparities.
- Despite significant upfront costs, pediatric epilepsy surgery offers long-term financial advantages and reduced healthcare resource utilization.
- Timely surgical intervention improves seizure control and cognitive outcomes with a low complication rate.
Conclusions:
- Interventions are necessary at family, provider, and healthcare system levels to enhance access to pediatric epilepsy surgery.
- Increasing access to pediatric epilepsy surgery can lead to improved patient outcomes and healthcare efficiencies.
Abstract:
Pediatric epilepsy surgery is underutilized. Only 1%-11% of children with drug resistant epilepsy (DRE) undergo surgical treatment, or less than half of those estimated to benefit. We conducted a systematic review of articles published in PubMed, EMBASE, and Web of Science in order to study the factors related to surgery underutilization as well as the impact on both the individual and the healthcare system. Our review demonstrates multiple factors leading to underutilization, including family misconceptions about epilepsy surgery, lack of provider knowledge, as well as systemic health disparities. While the upfront cost of epilepsy surgery is significant, the long-term financial benefits and reduced health resource utilization tilt the economic advantage in favor of surgery in children with DRE. Additionally, timely interventions improve seizure and cognitive outcomes with low risk of complications. Further interventions are needed at the levels of family, provider, and the healthcare system to increase access to pediatric epilepsy surgery.
More Related Videos
06:04Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
Published on: August 16, 2024
05:54Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
Published on: June 13, 2016
Related Concept Videos
Psychosurgery
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Metabolism