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Related Experiment Video

Updated: Oct 17, 2025

Delivery of Modified mRNA in a Myocardial Infarction Mouse Model

Delivery of Modified mRNA in a Myocardial Infarction Mouse Model

Published on: June 11, 2020

[Non-coding RNAs in viral myocarditis].

Jie Hu¹, Yangyang Zhu¹, Qiong Yuan¹

¹Institute of Pharmaceutical Innovation, College of Medicine, Wuhan University of Science and Technology, Wuhan 430065, Hubei, China.

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology

|October 8, 2021

Summary

Viral myocarditis (VMC) involves heart inflammation from viral infections. Non-coding RNAs (ncRNAs) show promise as new diagnostic and therapeutic targets for VMC, offering potential treatment avenues.

Keywords:

coxsackievirus non-coding RNAs pathogenesis therapeutic target viral myocarditis

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Last Updated: Oct 17, 2025

Delivery of Modified mRNA in a Myocardial Infarction Mouse Model

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Published on: June 11, 2020

In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge

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Preparation of a Non-Cardiomyocyte Cell Suspension for Single-Cell RNA Sequencing from a Post-Myocardial Infarction Adult Mouse Heart

Preparation of a Non-Cardiomyocyte Cell Suspension for Single-Cell RNA Sequencing from a Post-Myocardial Infarction Adult Mouse Heart

Published on: February 3, 2023

Area of Science:

Cardiology
Molecular Biology
Genetics

Background:

Viral myocarditis (VMC) is myocardial inflammation due to viral infection.
Current understanding of VMC pathogenesis is incomplete, complicating diagnosis and treatment.
Non-coding RNAs (ncRNAs) are emerging as key regulators in various biological processes.

Purpose of the Study:

To review recent findings on the role of ncRNAs in VMC.
To explore ncRNAs as potential diagnostic biomarkers for VMC.
To identify ncRNAs as novel therapeutic targets for VMC management.

Main Methods:

Literature review of recent studies on ncRNAs and VMC.
Analysis of research investigating ncRNA involvement in VMC pathogenesis.
Synthesis of data on ncRNA expression and function in VMC.

Main Results:

ncRNAs play significant roles in the development and progression of VMC.
Specific ncRNAs are differentially expressed in VMC patients, suggesting diagnostic potential.
Modulation of ncRNA activity could impact VMC pathology.

Conclusions:

ncRNAs are critically involved in VMC pathogenesis.
ncRNAs represent promising targets for VMC diagnosis and therapy.
Further research into ncRNA mechanisms will advance VMC treatment strategies.