Osteogenic sarcoma of the maxilla and mandible

Osteogenic sarcoma of the maxilla and mandible is a peculiar entity within the context of the malignant bone tumors of other sites. In our series of nine cases the mean age at appearance was 34.1 years; 44.5% of the tumors affected the maxilla, and 55.5% affected the mandible. Most of the tumors were principally rapidly growing and painless or minimally painful masses. Histopathologically, the fibroblastic type was the most frequent, with prevalence of Broders' Grades III and IV. Radical surgery was the only therapeutic procedure in 87.5% of the series, producing a survival of 85%. Overall survival for all the therapeutic categories was 75%, with a mean disease-free interval of 8 years. In the remaining cases, local recurrence and intracranial invasion were the main causes of death.