Related Experiment Video

Updated: Oct 17, 2025

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
08:55

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis

Published on: August 7, 2018

11.0K

Necroptosis and tumor progression.

Jiong Yan1, Peixing Wan1, Swati Choksi1

  • 1Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Trends in Cancer
|October 10, 2021
PubMed
Summary

Necroptosis, a programmed cell death, defends against pathogens and inflammation. Targeting necroptosis shows promise for novel cancer therapies by impacting tumor growth and spread.

Keywords:
MLKLRIPK3ZBP1antitumor immunitymetastasisnecroptosistumorigenesis

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