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Updated: Oct 17, 2025

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Methodology for Sputum Induction and Laboratory Processing
Published on: December 17, 2017
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Non-neoplastic respiratory fluid cytology including cell differential counts for interstitial lung disease
1Department of Histopathology, Royal Brompton Hospital, London, UK.
Abstract:
Bronchioloalveolar lavage (BAL) is a non-invasive and well-tolerated procedure that plays a key role in the diagnosis of a variety of non-neoplastic pulmonary diseases, including acute respiratory failure, infection, diffuse parenchymal lung disease (DLPD), paediatric and occupational lung disease, and in the evaluation of the lung allograft. A variety of analytic techniques are commonly performed on BAL fluid, including cytology, cell differential count, microbiology and virology, as well as a number of additional techniques in specific circumstances.

