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[A case of pustular psoriasis preceded by liver dysfunction]
Ryuichi Morita1, Masanobu Katayama1, Mayuko Nakanishi1
1Department of Gastroenterology, Saiseikai Shiga Hospital.
Summary
This rare case highlights pustular psoriasis, an intractable skin disease, occurring alongside pneumonia. Notably, liver dysfunction preceded the characteristic skin eruption, a reversal of the typical disease progression.
Area of Science:
- Dermatology
- Hepatology
- Internal Medicine
Background:
- Pustular psoriasis is a rare, intractable skin disease characterized by fever and sterile pustules.
- This condition is often associated with liver dysfunction, typically manifesting after skin symptoms appear.
Observation:
- A female patient in her thirties developed pustular psoriasis during pneumonia treatment.
- The patient presented with elevated serum total bilirubin levels, indicating liver dysfunction.
Findings:
- This case presents a rare instance where liver dysfunction preceded the onset of pustular psoriasis symptoms.
- The typical disease progression, where liver issues follow skin eruption, was reversed.
Implications:
- This case expands the understanding of pustular psoriasis's clinical spectrum and its association with liver dysfunction.
- It suggests a need for vigilance regarding liver function in patients presenting with pustular psoriasis, even before typical skin manifestations.
- Further research may elucidate the mechanisms behind this reversed temporal relationship in pustular psoriasis and liver involvement.
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