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Isolation of Valvular Endothelial Cells
Published on: December 29, 2010
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Ischemic hepatitis with infectious endocarditis: A case report.
Hiroshi Okano1, Ryo Okado2, Hisato Ito3
1Department of Gastroenterology, Suzuka General Hospital, Suzuka, Mie 513-8630, Japan.
Biomedical Reports
|October 11, 2021
Summary
Infectious endocarditis can cause liver damage through embolization, leading to ischemic hepatitis. This case highlights the importance of monitoring for whole organ ischemic complications in endocarditis patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Hepatology
Background:
- Infectious endocarditis is a serious infection affecting heart valves.
- Complications can arise from septic emboli, potentially affecting various organs.
Observation:
- A patient with infectious endocarditis developed elevated liver enzymes and signs of acute liver failure.
- Hepatic magnetic resonance imaging revealed diffuse high intensity, suggestive of ischemic hepatitis.
- The liver injury resolved spontaneously, attributed to collateral blood supply.
Findings:
- The patient's hepatic injury was diagnosed as ischemic hepatitis, likely caused by emboli from mitral valve vegetation.
- Isolation of *Pseudomonas guariconensis* confirmed the causative agent of endocarditis.
- Spontaneous recovery of liver function was observed despite initial signs of acute hepatic failure.
Implications:
- This case underscores the potential for widespread ischemic organ damage, including the liver, secondary to infectious endocarditis.
- Clinicians should maintain a high index of suspicion for embolic complications in endocarditis patients.
- Early recognition and management of infectious endocarditis are crucial to prevent severe systemic sequelae.

