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Updated: Oct 17, 2025

Intravitreal Injections in the Ovine Eye
Published on: July 5, 2022
Intraocular therapy in noninfectious uveitis
Rocco Luigi Modugno1, Ilaria Testi2, Carlos Pavesio3,4
1Department of Neuroscience, Ophthalmology Unit, University of Padua, Padua, Italy.
Abstract:
Systemic corticosteroids and immunosuppressant agents are the mainstay of therapy for non-infectious uveitis (NIU). However, the risks associated with systemic administration and the need of delivering an effective and safe anti-inflammatory treatment targeted to the site of inflammation have prompt the use of local therapy in the management of NIU. This review will analyse the different local treatment options available, including corticosteroids, anti-vascular endothelial growth factor (VEGF), methotrexate and the recent biologics.
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