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Related Experiment Video

Updated: Oct 17, 2025

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Published on: March 8, 2018

Infantile hemangioma affecting the iris.

Susan J Robertson^1,2, James E Elder^3,4, Philip S Bekhor^1,4

¹Department of Dermatology, The Royal Children's Hospital, Parkville, Victoria, Australia.

Pediatric Dermatology

|October 11, 2021

Summary

This summary is machine-generated.

A rare iris hemangioma in an infant girl, alongside skin hemangiomas, highlights the need for visceral screening. Oral propranolol effectively treated all hemangiomas without complications.

Keywords:

hemangiomas/vascular tumors neonatal neoplasms-benign skin signs of systemic disease therapy-systemic

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Area of Science:

Ophthalmology
Pediatrics
Dermatology

Background:

Infantile hemangiomas are common, but intraocular involvement, particularly iris hemangiomas, is rare.
Intraocular hemangiomas often signify neonatal hemangiomatosis, increasing the risk of visceral lesions.
Concurrent diffuse cutaneous infantile hemangiomas and iris hemangiomas present a unique clinical scenario.

Purpose of the Study:

To report a rare case of concurrent iris and diffuse cutaneous infantile hemangiomas.
To emphasize the importance of visceral screening in infants with intraocular hemangiomas.
To evaluate the efficacy of oral propranolol in treating such lesions.

Main Methods:

A case study of an infant girl presenting with iris and cutaneous hemangiomas.
Clinical observation and diagnosis of infantile hemangiomas.
Treatment initiated with oral propranolol.

Main Results:

The infant presented with a left iris hemangioma and diffuse cutaneous infantile hemangiomas from day 2 of life.
Oral propranolol administration led to rapid and complete resolution of all hemangiomas.
No complications were observed during or after treatment.

Conclusions:

Iris hemangiomas, though rare, require thorough evaluation for associated visceral involvement.
Early diagnosis and prompt treatment with oral propranolol can be highly effective for infantile hemangiomas, including intraocular types.
This case underscores the critical role of comprehensive screening in managing neonatal hemangiomatosis.